The simple answer is, you can't get rid of it.  SPAM is inevitable.  The only thing to do is to filter it out with software, like Norton AntiSpam.  I actually used that myself for several months and found good success, but it really wasn't enough for me.  There had to be a better way.  Here's what I did:

Instead of filtering out unwanted email, I wanted to blacklist all SPAM.  I installed a product called CA AntiSpam, which searches your Outlook or Outlook Express for previously authorized email addresses and sticks them all in a whitelist of trusted folks.  Any other email got sent directly to email jail (Junk folder).  Of course you still have to do a quick scan of your SPAM once in a while to see if any new folks have sent you mail - then mark them as "Not Junk".

Being cheap (and the fact that I had already purchased Norton AntiSpam), I found that you could export the Safe List to a simple text file, uninstall CA AntiSpam, then import back into Outlook's Safe Senders list (about 4200 addresses).  And that's it.  No more SPAM in my inbox, ever!  All it took was using Outlook as my email client, a trial download of an AntiSpam software and some elbow grease.

Now that's my story and yours may differ.  Most folks don't want to go through the trouble so I suggest investing CA Antispam - about $30.  It's easy to use and works with other email clients.  Most importantly, you will segregate ALL your SPAM.  Best $30 you'll ever spend.

Check out CA AntiSpam here or contact me at bill@gatorpc.com with any questions.